72934-36-2, name is 1-(4-Chlorophenyl)cyclopropanamine, belongs to chlorides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. HPLC of Formula: C9H10ClN
To a slurry of tert-butyl 4-(4-chloro-6-(2,2,2-trifluoroethoxy)-l,3,5-triazin-2- ylamino)benzoate (3.6 g) andl-(4-chlorophenyl)cyclopropanamine (1.49 g) in THF (50 mL) was stirred for 5 hours at 80C. The precipitate was filtrated through a plug washing with THF to give acrude product that was purified by Biotage eluting with 4/1-hexane/ethyl acetate to give 1.8 g of tert-butyl 4-(4-(l-(4- chlorophenyl)cyclopropylamino)-6-(2,2,2-trifluoroethoxy)-l,3,5-triazin-2- ylamino)benzoate as a solid.
The synthetic route of 72934-36-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BRISTOL-MYERS SQUIBB COMPANY; WANG, Tao; ZHANG, Zhongxing; HAN, Ying; YIN, Zhiwei; SCOLA, Paul Michael; WO2014/116768; (2014); A1;,
Chloride – Wikipedia,
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