Related Products of 6775-78-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 6775-78-6, name is 6-Chloroimidazo[1,2-b]pyridazine belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
3-bromo-6-chloroimidazo[l,2-b]pyridazine (11-1) was synthesized as shown in scheme 11, wherein N-bromosuccinamide (19.2 g, 108 mmol) was added to a solution of chloro-imidazo[l,2- b]pyridazine (10-1) (15 g, 98 mmol) in DMF cooled to 00C. The resulting solution was stirred at 00C for 1 hour and the reaction mixture was then poured into 1.4L of stirring water at room temperature. The resulting yellow heterogeneous solution was then stirred at room temperature for one hour and the solids were then filtered and washed with hexanes. The solid was dried under vacuum over-night to yield 3- bromo-6-chloroimidazo[l,2-b]pyridazine (11-1) as a yellow solid.
The synthetic route of 6-Chloroimidazo[1,2-b]pyridazine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; IRM LLC; WO2009/140128; (2009); A2;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics