Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 102-49-8, name is 3,4-Dichlorobenzylamine, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 3,4-Dichlorobenzylamine
General procedure: The acid (9a?h) (1 mmol) and amine (1 mmol) were dissolvedin dimethylformamide (5v) under argon atmosphereand N-ethyl diisopropylamine (3 mmol) was added dropwise to it at 0 °C and HATU (1.3 mmol) was added lot wiseduring a period of 15 min. The reaction medium was slowlyallowed to reach room temperature and stirred for 4 h atroom temperature. The reaction progress was monitored byTLC. After completion of the reaction, the reaction mixturewas poured to ice cold water and stirred at room temperaturefor 30 min and the precipitated solid was filtered,washed with water and dried under vacuum. This crudeproduct was further purified by column chromatographyusing 2?5percent of methanol in chloroform to get the requiredamide.#10;
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 102-49-8.
Reference:
Article; Ajeesh Kumar; Bodke, Yadav D.; Lakra, Peter Serjious; Sambasivam, Ganesh; Bhat, Kishore G.; Medicinal Chemistry Research; vol. 26; 4; (2017); p. 714 – 744;,
Chloride – Wikipedia,
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