Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2106-02-7, name is 2-Chloro-4-fluoroaniline, A new synthetic method of this compound is introduced below., Safety of 2-Chloro-4-fluoroaniline
General procedure: A solution of salicylaldehyde derivative (1.0 equiv.) in ethanol (5.0 mL mmol-1)was added into a solution of aniline derivative (1.0 equiv.) in ethanol (5.0 mL mmol-1). After stirring at room temperature for 1 h, the mixture was refluxed until complete consumption of the starting materials. Subsequently, ethanol was removed under reduced pressure and the obtained imines were purified by crystallization. The obtained Schiff-bases were characterized by NMR and elemental analysis. All analytical data is in accordance with literature [21,26,30,32,33,43].
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Altmann, Philipp; Cokoja, Mirza; Kuehn, Fritz E.; Journal of Organometallic Chemistry; vol. 701; (2012); p. 51 – 55;,
Chloride – Wikipedia,
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