Application of 870-24-6, These common heterocyclic compound, 870-24-6, name is 2-Chloroethanamine hydrochloride, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
AEA was synthesised according to the method described by Jung et al. [22]. 2-chloroethylamine hydrochloride (5 g, 43 mmol) was ground and dissolved in deionised water (50 ml). Sodium azide (8 g, 123 mmol) was added and the mixture was heated at 80 C for 18 h. The solution was then made alkaline with potassium hydroxide (15 g), extracted using diethyl ether and dried over magnesium sulphate. Finally the solution was concentrated using rotary evaporation to give an amber coloured, viscous oil. AEA was characterised using 1H NMR and FTIR spectroscopy (See Fig. S1, Supporting information). The integrations for the peaks gave the correct proton ratios and the FTIR spectra (Fig. 2(a)) showed a strong azide band at 2100 cm-1.
Statistics shows that 2-Chloroethanamine hydrochloride is playing an increasingly important role. we look forward to future research findings about 870-24-6.
Reference:
Article; Farley, Robert; Saunders, Brian R.; Polymer; vol. 55; 2; (2014); p. 471 – 480;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics