Recently I am researching about HIGHLY EFFICIENT SYNTHESIS; CROSS-COUPLING REACTIONS; CARBOXYLIC-ACIDS; DECARBONYLATIVE BORYLATION; AMIDES; REDUCTION; ESTERS; CHLORIDES; TRANSAMIDATION; HYDROGENATION, Saw an article supported by the Science and Technology Planning Project of Guangdong Province [2017A010103017]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [51703069, 21272080]; Special Innovation Projects of Common Universities in Guangdong Province [20178S0182]. SDS of cas: 50-30-6. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: He, ZY; Wang, ZJ; Ru, JX; Wang, YL; Liu, TT; Zeng, Z. The CAS is 50-30-6. Through research, I have a further understanding and discovery of 2,6-Dichlorobenzoic acid
We report the catalytic reduction of both active esters and amides by selective C(acyl)-X (X=O, N) cleavage to access aldehyde functionality via a palladium-catalyzed strategy. Reactions are promoted by hydrosilanes as reducing reagents with good to excellent yields and with excellent chemoselectivity for C(acyl)-N and C(acyl)-O bond cleavage. Carboxylic acid C(acyl)-O bonds are activated by 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) to form triazine ester intermediates, which further react with hydrosilanes to yield aldehydes in one-pot two-step procedures. We demonstrate that C(acyl)-O cleavage/formylation offers higher yields and broader substrate scopes compared with C(acyl)-N cleavage under the same reaction conditions.
SDS of cas: 50-30-6. About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact He, ZY; Wang, ZJ; Ru, JX; Wang, YL; Liu, TT; Zeng, Z or concate me.
Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics