An article Online clean-up setup for the determination of non-fluorescent acidic pharmaceutical drugs in complex biological samples WOS:000488136700013 published article about NONSTEROIDAL ANTIINFLAMMATORY DRUGS; PERFORMANCE LIQUID-CHROMATOGRAPHY; SENSITIVE FLUORESCENCE DETERMINATION; COLUMN-SWITCHING TECHNIQUE; TANDEM MASS-SPECTROMETRY; METAL-ORGANIC FRAMEWORK; SOLID-PHASE EXTRACTION; ION CHROMATOGRAPHY; HUMAN SERUM; HPLC in [Muhammad, Nadeem; Cui, Hairong] Wuchang Univ Technol, Dept Environm Engn, Wuhan, Hubei, Peoples R China; [Muhammad, Nadeem; Guo, Dandan; Zhang, Yun; Subhani, Qamar] Zhejiang Univ, Dept Chem, Xixi Campus, Hangzhou 310028, Zhejiang, Peoples R China; [Guo, Dandan] Ningbo Univ, Inst Drug Discovery Technol, Ningbo 315211, Zhejiang, Peoples R China; [Intisar, Azeem; Qadir, Muhammad Abdul] Univ Punjab, Inst Chem, Lahore, Pakistan; [Subhani, Qamar] Higher Educ Dept, Lahore, Punjab, Pakistan in 2019, Cited 46. Computed Properties of C7H4Cl2O2. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0
Analysis of acidic pharmaceuticals in complex biological samples is a challenging and formidable task due to the existence of interfering constituents within the sample matrices. Therefore, in order to avoid analytical column clogging and suppression/enhancement of signals of the analyte of interest, herein a simple, cost-effective and quick online ion chromatography based clean-up setup was introduced. This system was further coupled with a cost-effective homemade photochemically induced fluorimetric (PIF) setup for direct online conversion of non fluorescent acidic pharmaceutical drugs into their respective fluorescent species. This advantageous system was favorably applied for the determination of four non-fluorescent acidic compounds in two complex biological samples (human serum and oral fluid) with minimum labor and organic solvent consumption. At optimized conditions, the developed method has shown good sensitivity, selectivity, satisfactory recoveries (88.68-102.14%) and low limits of detection (0.35-8.10 mu g/L) with minimum or zero matrix effect.
About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Muhammad, N; Guo, DD; Zhang, Y; Intisar, A; Subhani, Q; Qadir, MA; Cui, HR or concate me.. Computed Properties of C7H4Cl2O2
Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics