Recommanded Product: 95-49-8. I found the field of Chemistry; Science & Technology – Other Topics very interesting. Saw the article Cp*Co(iii) and Cu(OAc)(2) bimetallic catalysis for Buchwald-type C-N cross coupling of aryl chlorides and amines under base, inert gas & solvent-free conditions published in 2020.0, Reprint Addresses Joshi, RK (corresponding author), Malaviya Natl Inst Technol, Dept Chem, Jaipur 302017, Rajasthan, India.. The CAS is 95-49-8. Through research, I have a further understanding and discovery of 1-Chloro-2-methylbenzene.
A strategy involving bimetallic catalysis with a combination of Cp*Co(CO)I-2 and Cu(OAc)(2) was used for performing Buchwald-type C-N coupling reactions of aryl chlorides with amines. The reactions proceeded at 100 degrees C to produce excellent yields of many of the desired C-N coupled products, in 4 h, under aerobic reaction conditions. The reactions were shown to run under base-free and solvent-free conditions, enabling this strategy to work efficiently for electron-withdrawing and base-sensitive functionalities. The presented methodology was found to be equally efficient for electron-donating functionalities as well as for primary (1 degrees) and secondary (2 degrees) aromatic and aliphatic amines. Moreover, the products were easily separated through the extractions of the organic aqueous layer, with this process chromatographic separations is not required.
Recommanded Product: 95-49-8. About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Srivastava, AK; Sharma, C; Joshi, RK or concate me.
Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
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