What I Wish Everyone Knew About 1145671-36-8

In some applications, this compound(1145671-36-8)HPLC of Formula: 1145671-36-8 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines, published in 2019, which mentions a compound: 1145671-36-8, mainly applied to anti tubercular anilinoquinoline anilinoquinazoline, HPLC of Formula: 1145671-36-8.

We screened a series of 4-anilinoquinolines and 4-anilinoquinazolines and identified novel inhibitors of Mycobacterium tuberculosis (Mtb). The focused 4-anilinoquinoline/quinazoline scaffold arrays yielded compounds with high potency and the identification of 6,7-dimethoxy-N-(4-((4-methylbenzyl)oxy)phenyl)quinolin-4-amine (34) with an MIC90 value of 1.25-2.5 μM. We also define a series of key structural features including the benzyloxy aniline and the 6,7-dimethoxy quinoline ring that are important for Mtb inhibition. Importantly the compounds showed very limited toxicity and scope for further improvement by iterative medicinal chem.

In some applications, this compound(1145671-36-8)HPLC of Formula: 1145671-36-8 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics