The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol( cas:35836-73-8 ) is researched.Recommanded Product: 2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol.McLaughlin, Mark L.; McKinney, Jeffrey A.; Paquette, Leo A. published the article 《Chemistry of isodicyclopentadienes. Part 36. Efficient preparation of homochiral bicyclo-annulated cyclopentadienes via the Skatteboel rearrangement. Avoidance of limitations due to angle strain》 about this compound( cas:35836-73-8 ) in Tetrahedron Letters. Keywords: cyclopentadiene annulation nopol camphor. Let’s learn more about this compound (cas:35836-73-8).
(1R)-(-)-Nopol and (1R)-(+)-camphor are both vinylated in 2 steps to give vinylbicycloheptenes I and II. Dibromocyclopropanation followed by carbene formation with MeLi leads to optically pure annulated cyclopentadienes in ∼40% overall yield.
Here is just a brief introduction to this compound(35836-73-8)Recommanded Product: 2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol, more information about the compound(2-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethanol) is in the article, you can click the link below.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics