The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-(3,4-Dihydroquinolin-1(2H)-yl)ethanamine, is researched, Molecular C11H16N2, CAS is 37481-18-8, about Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays, the main research direction is food intake reduction 5HT2C receptor agonists lead; 5-HT(2C) receptor; Agonist; GPCR; Lead identification.Recommanded Product: 37481-18-8.
A series of potential new 5-HT2 receptor scaffolds based on a simplification of the clin. studied, 5-HT2CR agonist vabicaserin, were designed. An in vivo feeding assay early in our screening process played an instrumental part in the lead identification process, leading us to focus on a 6,5,7-tricyclic scaffold. A subsequent early SAR investigation provided potent agonists of the 5-HT2C receptor that were highly selective in both functional and binding assays, had good rat PK properties and that significantly reduced acute food intake in the rat.
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Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics