The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Piperidine-3-carboxylic acid, is researched, Molecular C6H11NO2, CAS is 498-95-3, about RASS-Enabled S/P-C and S-N Bond Formation for DEL Synthesis, the main research direction is RASS enabled bond formation DNA encoded library; DNA encoded library; nickel cross-coupling; reversible adsorption to solid support; sulfonamide; sulfone.Quality Control of Piperidine-3-carboxylic acid.
DNA encoded libraries (DEL) showed promise as a valuable technol. for democratizing the hit discovery process. Although DEL provides relatively inexpensive access to libraries of unprecedented size, their production has been hampered by the idiosyncratic needs of the encoding DNA tag relegating DEL compatible chem. to dilute aqueous environments. Recently reversible adsorption to solid support (RASS) has been demonstrated as a promising method to expand DEL reactivity using standard organic synthesis protocols. Here the authors demonstrate a suite of on-DNA chemistries to incorporate medicinally relevant and C-S, C-P and N-S linkages into DELs, which are underrepresented in the canonical methods.
In addition to the literature in the link below, there is a lot of literature about this compound(Piperidine-3-carboxylic acid)Quality Control of Piperidine-3-carboxylic acid, illustrating the importance and wide applicability of this compound(498-95-3).
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics