The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《N1- and N4-Substituted sulfanilamides. I》. Authors are De, S. C.; Datta, P. K..The article about the compound:Thiazole-2,4-diamine hydrochloridecas:72792-54-2,SMILESS:NC1=NC(N)=CS1.[H]Cl).Application In Synthesis of Thiazole-2,4-diamine hydrochloride. Through the article, more information about this compound (cas:72792-54-2) is conveyed.
A note stating the various derivatives made by combining heterocyclic rings (pyrazolone, hydroxypyrimidine, and thiazole) with the N1 and N4 of sulfanilamide. The following compounds were prepared 1-(p-Sulfamylphenyl)-3-methyl-5-pyrazolone, m. 246°; 1-(p-sulfamylphenyl)-3-methyl-4-(p-sulfamylazobenzene)-5-pyrazolone, m. 298°; 1-(p-carboxyphenyl)-3-methyl-5-pyrazolone, m. 278°; 1-(p-carboxyphenyl)-3-methyl-4-(p-sulfamylazobenzene)-5-pyrazolone, m. 291°; 1-(p-sulfophenyl)-3-methyl-5-pyrazolone, m. 306°; 1-(p-sulfophenyl)-3-methyl-4-(p-sulfamylazobenzene)-5-pyrazolone, m. above 320°; N1-antipyryl-N4-acetylsulfanilamide, m. 265°; N1-antipyrylsulfanilamide, m. 249°; 4-(p-sulfamylazobenzene)-3-amino-5-pyrazolone, m. 274°; 2-(N-acetylsulfanilyl)-3-methyl-5-pyrazolone, m. 195°; 2-sulfanilyl-3-methyl-5-pyrazolone, m. 169°; 1-(N-acetylsulfanilyl)-3-methyl-5-pyrazolone, m. 167°; 2,4-diaminothiazole hydrochloride; 2,4-diamino-5-(sulfamylazobenzene)thiazole, m. 185°; 2,4-diamino-6-hydroxy-5-pyrimidyl(p-sulfamylazobenzene), m. above 300°; sulfanilylguanidine, m. 189°. Details to be published.
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Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics