Foye, William O.; Ghosh, Krishnendu published an article about the compound: Thiazole-2,4-diamine hydrochloride( cas:72792-54-2,SMILESS:NC1=NC(N)=CS1.[H]Cl ).Application of 72792-54-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:72792-54-2) through the article.
Bis(methylthio) and methylthio amino derivatives of 1-methylpyridinium (and quinolinium)-2-dithioacetic acids, found to have protective activity in mice vs. LDs of γ-radiation, were converted to Cu(II) complexes. The complexes were isolated as double salts with CuCl2, and some were sufficiently soluble to be assayed for superoxide dismutase (SOD) activity. This was done by measuring the inhibition of the superoxide reduction of nitroblue tetrazolium. A pos. correlation was found in both the pyridinium and quinolinium series between the extent of SOD activity and the degree of radiation protection. This provides evidence for a mechanism of whole body radiation protection, based on the ability to dismutate superoxide. Copper complexes of a variety of other heterocyclic ligands showed much less ability to mimic SOD activity.
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Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics