Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Organic Chemistry Frontiers called Regioselective C-H alkylation and alkenylation at the C5 position of 2-amino-1,4-naphthoquinones with maleimides under Rh(III) catalysis, Author is Yakkala, Prasanna Anjaneyulu; Giri, Deepesh; Chaudhary, Bharatkumar; Auti, Prashant; Sharma, Satyasheel, which mentions a compound: 4144-22-3, SMILESS is O=C(C=C1)N(C(C)(C)C)C1=O, Molecular C8H11NO2, Safety of 1-(tert-Butyl)-1H-pyrrole-2,5-dione.
Rhodium(III) catalyzed regioselective C-H alkylation and alkenylation at the C5 position of 1,4-naphthoquinones I [R1 = H, Me, Et; R2 = CH3(CH2)3, 4-FC6H4CH2, cyclohexylmethyl, etc.; R1R2 = -(CH2)4-, -(CH2)5-; R3 = H, Cl] with maleimides II (R = H, Me, C6H5CH2, C6H5, etc.) under acidic and basic conditions, resp., is described. The alkylamino substituents at the C2 position enabled the reaction to proceed efficiently. The alkylation reaction proceeds via a redox neutral Rh(III) pathway, whereas the alkenylation reaction takes place through the typical redox Rh(III) pathway to yield Rh(I) species.
After consulting a lot of data, we found that this compound(4144-22-3)Safety of 1-(tert-Butyl)-1H-pyrrole-2,5-dione can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics