The important role of 498-95-3

The article 《Synthesis and biological evaluation of α- and β-hydroxy substituted amino acid derivatives as potential mGAT1-4 inhibitors》 also mentions many details about this compound(498-95-3)Name: Piperidine-3-carboxylic acid, you can pay attention to it, because details determine success or failure

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis and biological evaluation of α- and β-hydroxy substituted amino acid derivatives as potential mGAT1-4 inhibitors, published in 2020-08-31, which mentions a compound: 498-95-3, Name is Piperidine-3-carboxylic acid, Molecular C6H11NO2, Name: Piperidine-3-carboxylic acid.

Abstract: In this study, we report the synthesis and biol. evaluation of a variety of α- and β-hydroxy substituted amino acid derivatives as potential amino acid subunits in inhibitors of GABA uptake transporters (GATs). In order to ensure that the test compounds adopt a binding pose similar to that presumed for related larger GAT inhibitors, lipophilic residues were introduced either at the amino nitrogen atom or at the alc. function. Several of the synthesized compounds were found to exhibit similar inhibitory activity at the GAT subtypes mGAT2, mGAT3, and mGAT4, resp., as compared with the reference N-butylnipecotic acid. Hence, these compounds might serve as starting point for future developments of more complex GAT inhibitors.

The article 《Synthesis and biological evaluation of α- and β-hydroxy substituted amino acid derivatives as potential mGAT1-4 inhibitors》 also mentions many details about this compound(498-95-3)Name: Piperidine-3-carboxylic acid, you can pay attention to it, because details determine success or failure

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics