The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-(tert-Butyl)-1H-pyrrole-2,5-dione( cas:4144-22-3 ) is researched.Category: chlorides-buliding-blocks.Yang, Xiu-Long; Guo, Jia-Dong; Lei, Tao; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu published the article 《Oxidative Cyclization Synthesis of Tetrahydroquinolines and Reductive Hydrogenation of Maleimides under Redox-Neutral Conditions》 about this compound( cas:4144-22-3 ) in Organic Letters. Keywords: fused tetrahydroquinoline preparation; aniline maleimide oxidative cyclization photocatalyst. Let’s learn more about this compound (cas:4144-22-3).
A redox-neutral reaction without using any external oxidant and reductant in one pot is described. By combining a Ru(bpy)32+ photocatalyst and cobaloxime catalyst, a number of tertiary anilines can be oxidized by Ru(bpy)32+ to realize oxidative cyclization of tetrahydroquinolines, and the electron and proton eliminated from the substrate anilines are captured by a cobaloxime catalyst to achieve hydrogen transfer in situ to maleimides, in good to excellent yields, under redox-neutral conditions.
Different reactions of this compound(1-(tert-Butyl)-1H-pyrrole-2,5-dione)Category: chlorides-buliding-blocks require different conditions, so the reaction conditions are very important.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics