Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. HPLC of Formula: 349-88-2.
Baker, Rachel J.;Ching, Justin;Hou, Teh Ren;Franzoni, Ivan;Lautens, Mark research published 《 Dearomative Cyclopropanation of Naphthols via Cyclopropene Ring-Opening》, the research content is summarized as follows. The dearomatization of 2-naphthols represents a simple method for the construction of complex 3D structures from simple planar starting materials. A cyclopropanation of 2-naphthols that proceeds via cyclopropene ring-opening using rhodium and acid catalysis under mild conditions is described. The vinyl cyclopropane mols. were formed with high chemoselectivity and scalability, which could be further functionalized at different sites. Both computational and exptl. evidence were used to elucidate the reaction mechanism.
HPLC of Formula: 349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.
4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.
4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics