Chloride substituents modify the physical properties of organic compounds in several ways. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Safety of (2-Chlorophenyl)boronic acid.
Cai, Mingzhong;Xie, Gang;Xu, Zhaotao;Huang, Bin research published 《 Recyclable palladium-catalyzed Suzuki coupling of aromatic triazine esters: A practical one-pot synthesis of aryl ketones from aromatic acids》, the research content is summarized as follows. An efficient heterogeneous palladium-catalyzed Suzuki coupling of aromatic triazine esters I (Ar = 4-methylphenyl, naphthalen-1-yl, thiophen-2-yl, etc.) with arylboronic acids Ar1B(OH)2 (Ar1 = Ph, 3,5-dichlorophenyl, furan-2-yl, etc.) has been developed. The reaction proceeds smoothly in toluene at 110°C using 2 mol% of MCM-41-bound bidentate phosphine palladium complex [MCM-41-2P-Pd(OAc)2] as catalyst and provides a novel and practical method for the synthesis of aryl ketones ArC(O)Ar1 starting from readily available aromatic acids ArCOOH in a one-pot procedure with moderate to excellent yields. The MCM-41-2P-Pd(OAc)2 catalyst can be reused at least seven times without any apparent decrease in its catalytic activity.
3900-89-8, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., Safety of (2-Chlorophenyl)boronic acid
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics