Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Category: chlorides-buliding-blocks.
Deng, H.;Liao, W.;Tan, X.;Liu, T. research published 《 SYNTHESIS, CHARACTERIZATION, CRYSTAL STRUCTURE, AND DFT STUDY OF 3-BROMO-N- (3-FLUOROPHENYL)BENZENESULFONAMIDE》, the research content is summarized as follows. Sulfonamides are used as antibacterial drugs for decades. 3-bromo-N-(3-fluorophenyl) benzenesulfonamide is synthesized by the amidation reaction. The structure of the title compound is confirmed by FTIR, 1H and 13C NMR, and MS spectroscopies. At the same time, the single crystal of the compound is analyzed by X-ray diffraction and the conformational anal. is performed. D. functional theory (DFT) is used to further calculate the mol. structure, and the results are consistent with the X-ray diffraction results. In addition, DFT is also used to calculate and analyze the electrostatic potential and the frontier MO of the mol., which provides some references for the anal. of the phys. and chem. properties of the mol. In addition, vibrational frequencies are analyzed, revealing some physicochem. properties of the title compound
2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Category: chlorides-buliding-blocks
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics