Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Related Products of 104-86-9.
Dhananjaya, G.;Venkateshwarlu, Rapolu;Dinne, Naresh Kumar Reddy;Kumar, Avula Mahesh;Mekala, Ramamohan;Anna, Venkateswara Rao;Kapavarapu, Ravikumar;Pal, Manojit research published 《 Wang-OSO3H catalyzed green synthesis of bioactive isoindolo[2,1-a]quinazoline-5,11-dione derivatives: An unexpected observation》, the research content is summarized as follows. The sulfonic acid-functionalized Wang resin (Wang-OSO3H) was explored as a polymeric and recoverable acidic catalyst for the synthesis of isoindolo[2,1-a]quinazoline-5,11-diones I (R1 = H, Cl, Br; R2 = Me, HCCCH2, cyclopropyl, 2-MeOC6H4, etc.) under green conditions. Thus, the Wang-OSO3H catalyzed multicomponent reaction (MCR) of an R1-substituted isatoic anhydride, 2-formylbenzoic acid and various amines R2NH2 in pure water afforded a range of desired products I in good to excellent (86-94%) yields. The methodol. could be performed under open air and is amenable for scale-up synthesis. The catalyst could be recovered and recycled for several times without significant loss of its catalytic activity. The unexpected formation of 2-(1-hydroxy-3-oxoisoindolin-2-yl)benzamide derivative as observed in one case may allow the access of this class of heterocycles from the same MCR by using an appropriate amine. In silico assessment suggested that the compound I (R1 = H; R2 = 4-MeOC6H4CH2), a known inhibitor of TNF-α, could be a potential ligand for SARS-CoV-2 with which it formed H-bonds through its OMe and two C=O groups.
Related Products of 104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics