Chloride substituents modify the physical properties of organic compounds in several ways. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Formula: C7H4Cl2O.
Enbaraj, E.;Dhineshkumar, E.;Jeyashri, K. R.;Logeshwari, G.;Devi, V. J. Ramya;Manikandan, H.;Seenivasan, M.;Rajathi, V.;Chakkaravarthy, J.;Govindaraju, R. research published 《 Novel synthesis of NE,N’E-4,4′-sulfonylbis(N-substituted-dichlorobenzylidene)anilines derivative their application biological and DFT studies》, the research content is summarized as follows. The synthesized compounds I (R1 = H, Cl; R2 = H; R3 = H, Cl; R4 = H, Cl; R5 = H, Cl) were evaluated for their in vitro activity against several microbes. Compound I exhibited potent antibacterial activity with the reference standard ciprofloxacin and fluconazol. In the ground-state, compounds I mol. geometries were determined using the DFT based on B3LYP/6-31G(d,p) and compared to the exptl. results. In addition, compounds I, MEP maps and mol. frontier orbitals were performed, and the results obtained were compatible with the electronic properties.
6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., Formula: C7H4Cl2O
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics