The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Name: (4-Chlorophenyl)methanamine.
Fu, Yiwei;Shi, Haoyu;Lei, Shengshu;Shi, Lei;Li, Hao research published 《 Cu catalyzed [4 + 2] cycloaddition for the synthesis of highly substituted 3-fluoropyridines》, the research content is summarized as follows. A copper catalyzed annulation-aromatization of benzyl trifluoromethyl ketimines with 3-acryloyloxazolidin-2-ones for the synthesis of 3-fluoropyridines I [R = H, 3-Cl, 3-Me, etc.; R1 = H, 4-Cl, 4-MeO, etc.; R2 = 2-oxopyrrolidin-1-yl, 2-oxooxazolidin-3-yl, 2-oxo-3-phenyl-imidazolidin-1-yl, etc.] through double C-F bond cleavages had been developed. In this approach, the annulation occurred between the in situ formed dienes from trifluoromethyl ketimines via the first C-F bond cleavage and 3-acryloyloxazolidin-2-ones. Then the aromatization afforded 3-fluoropyridines I in moderate yields through the second C-F bond cleavage. The 3-fluoropyridine products I [R = R1 = H; R2 = 2-oxooxazolidin-3-yl] could be further hydrolyzed to multi-substituted 3-pyridinecarboxylic acids.
Name: (4-Chlorophenyl)methanamine, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics