Recommanded Product: (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets)In 2017, Hylse, Ondrej;Maier, Lukas;Kucera, Roman;Perecko, Tomas;Svobodova, Aneta;Kubala, Lukas;Paruch, Kamil;Svenda, Jakub published 《A Concise Synthesis of Forskolin》. 《Angewandte Chemie, International Edition》published the findings. The article contains the following contents:
A 24-step synthesis of (±)-forskolin (I) is presented, which delivered hundred milligram quantities of this complex diterpene in one pass. Transformations key to our approach include: (a) a strategic allylic transposition, (b) stepwise assembly of a sterically encumbered isoxazole ring, and (c) citric acid-modified Upjohn dihydroxylation of a resilient tetrasubstituted olefin. The developed route has exciting potential for the preparation of new forskolin analogs inaccessible by semisynthesis. And (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) was used in the research process.
(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Recommanded Product: (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets)) is used as a resolving agent for alcohols as the diastereomeric esters by crystallization or chromatography and as a chiral derivatization reagent for determination of enantiomeric excess of alcohols and amines.
Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics