Singh, Gurjaspreet et al. published new experimental results with the assistance of cas: 7791-11-9

Singh, Gurjaspreet;Priyanka;Sushma;Pawan;Diksha;Suman;Mohit;Devi, Anita;Gupta, Sofia published 《Tetrazole conjoined organosilane and organosilatrane via the ‘click approach’: a potent Mycobacterium tuberculosis enoyl ACP reductase inhibitor and a dual sensor for Fe(III) and Cu(II) ions》. The research results were published in《New Journal of Chemistry》 in 2022.Product Details of 7791-11-9 The article conveys some information:

Tetrazoles are a class of heterocycles that are important in medicinal chem. and drug design due to their metabolic stability and other beneficial physicochem. properties. Organosilicon chem. is an amalgamation of different moieties and has vast applications. The amalgamation of pharmacol. active tetrazole segments with optically active higher coordinated silicon atoms can synergistically enhance their applicability in certain fields. As such, in this article, we have designed and synthesized a novel series of tetrazole conjoined organosilane and organosilatrane using ZnBr₂ as a catalyst via the click reaction. The all new compounds were confirmed using IR, ¹H NMR and ¹³C NMR and mass spectrometry. The designed tetrazole appended organosilatrane (3) was explored for recognition potential and found to be specific and selective for Fe(III) and Cu(II) metal ions. The low detection limits, high association constants, negligible competitive interference and reversible behavior of the sensor confirm its recognition efficiency only towards Fe(III) and Cu(II). Job’s plot confirmed the 1 : 1 stoichiometric binding of the host : guest system. To explore the biol. results of tetrazole-based organosilatrane, a mol. docking study with the enoyl acyl carrier protein reductase of Mycobacterium tuberculosis was performed and the selected ligand was found to have a good docking score with a binding energy of -7.82 kcal mol^-1.Rubidiumchloride (cas: 7791-11-9) were involved in the experimental procedure.

Rubidium chloride(cas: 7791-11-9) is the mostly used rubidium compound, and finds use in various fields ranging from electrochemistry to molecular biology.Product Details of 7791-11-9 It is an efficient non-invasive biomarker; increases dopamine and norepinephrine levels, and useful for anergic and apathetic depressives.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics