Month: September 2022

Chloride substituents modify the physical properties of organic compounds in several ways. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Related Products of 104-86-9.

Bai, Xueying;Huang, Liliang;Qing, Bin;Zuo, Zhicheng;Feng, Huangdi research published 《 Catalyst-Free Hydrogen Proton Transfer Reduction of Nitrobenzamides to Aminobenzamides with i-PrOH/KOH System》, the research content is summarized as follows. A reduction of nitrobenzenes via the combination of KOH and isopropanol was established for the general synthesis of aniline derivatives A metal catalyst isn’t required in this alternative reduction reaction, and a series of nitrobenzamide compounds RC₆H₄C(O)NHR¹ (R = 2-NO₂, 3-NO₂, 4-NO₂; R¹ = 4-bromobenzyl, 2,6-diisopropylphenyl, 3-methoxybenzyl, etc.) were chemoselectively reduced into the corresponding aminobenzamides RC₆H₄C(O)NHR¹ (R = 2-NH₂, 3-NH₂, 4-NH₂) in good to excellent yields. This reaction is operationally simple, and proceeds under mild conditions.

104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., Related Products of 104-86-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. SDS of cas: 2905-24-0.

Bai, Rubing;Wang, Pei;Meng, Xianwen;He, Lei research published 《 Sky-blue-emitting cationic iridium complexes with oxadiazole/triazine-type counter-anions and their use for efficient solution-processed organic light-emitting diodes》, the research content is summarized as follows. Counter-anion control has emerged as a facile approach to tune the properties of cationic iridium complexes for optoelectronic applications. Here we report sky-blue-emitting cationic iridium complexes with electron-deficient oxadiazole/triazine-type counter-anions and their use for highly efficient solution-processed organic light-emitting diodes (OLEDs). A sky-blue-emitting complex [Ir(meoppy)₂(dmapzpy)]⁺ (meoppy is 4-methoxy-2-phenylpyridine and dmapzpy is 4-dimethylamino-2-(1H-pyrazol-1-yl)pyridine) has been developed as the phosphorescent cation. Hexafluorophosphate (PF^–₆), 3,5-bis(5-(4-(tert-butyl)phenyl)-1,3,4-oxadiazol-2-yl)benzenesulfonate (OXD-7-SO^–₃), 4-(4,6-diphenyl-1,3,5-triazin-2-yl)benzenesulfonate (TRZ-p-SO^–₃) and 3-(4,6-diphenyl-1,3,5-triazin-2-yl)benzenesulfonate (TRZ-m-SO^–₃) have been developed as the counter-anions in complexes R, 1, 2 and 3, resp. In doped films, the complexes afford similar sky-blue emission peaked at around 472 nm with high phosphorescent efficiencies of around 0.80. Solution-processed, double-layer OLEDs using the complexes as dopants afford sky-blue electroluminescence peaked at around 476 nm. The devices using complexes 1-3 show largely enhanced performances compared to the device using the reference complex R, owing to the improved carrier-recombination balance imparted by the electron-trapping effects of the oxadiazole/triazine type counter-anions. The devices based on complexes 2 and 3 exhibit higher performances than that based on complex 1, because of the stronger electron-trapping effects of TRZ-p-SO^–₃ and TRZ-m-SO^–₃ compared to OXD-7-SO^–₃. The double-layer device using complex 3 shows a peak current efficiency of 29.4 cd A^-1 and an external quantum efficiency of 12.4%, which are the highest for blue OLEDs using cationic iridium complexes reported so far.

2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., SDS of cas: 2905-24-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Safety of 4-Fluorobenzene-1-sulfonyl chloride.

Babu, Sakamuri Sarath;Gopinath, Purushothaman research published 《 Photomediated Tandem Sulfonyl Addition-Chemoselective N-Cyclization of o-Alkenyl Aryl Ureas: Direct Assembly of Functionalized Dihydroquinazolinones》, the research content is summarized as follows. Photoredox-mediated tandem addition-chemoselective cyclization of o-alkenyl aryl ureas was reported for the synthesis of sulfonyl and activated alkyl-decorated dihydroquinazolinones I [R = Et, Bn, 4-MeC₆H₄, etc.; R¹ = Et, Bn, CH₂-4-MeOC₆H₄; R² = CH₂CN, SO₂Et, SO₂-4-MeC₆H₄, etc.]. By a careful choice of o-alkenyl aryl urea starting materials, chemoselective N-cyclization in the presence of more reactive amidic oxygen was achieved. The scope of the methodol. with a variety of sulfonyl chlorides and activated alkyl halides was discussed. Finally, large-scale synthesis of sulfonyl-substituted dihydroquinazolinone showcased the synthetic utility of the methodol.

Safety of 4-Fluorobenzene-1-sulfonyl chloride, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Formula: C6H4BrClO2S.

Babu, Gogu V. Surendra;Bhaskaran, Aathira;Sridhar, Balasubramanian;Rao, Tumula Venkateshwar;Parvathaneni, Sai Prathima research published 《 Ullmann Coupling Reaction of Bicyclic Amidines DBU/DBN with Aryl Halides: A Pathway to the Synthesis of ε-Caprolactam Derivatives》, the research content is summarized as follows. This paper demonstrated a selective, mild approach to copper iodide catalyzed Ullmann amination of aryl halides to synthesize N-alkylated derivatives of ε-caprolactam I [R = Ph, 4-ClC₆H₄, 3-pyridyl, etc; n = 1, 3]. The synthetic route involved an in-situ ring-opening of 1,8-diazabicyclo[5.4.0]undec-8-ene (DBU) followed by concurrent arylation with aryl halides in the presence of copper iodide as a catalyst under ligand-free conditions. This method provided wide variety of ε-caprolactam derivatives I in good to excellent yields in a single synthetic sequence. Similarly, other bicyclic amidines such as 1,5-diazabicyclo-[4.3.0]non-5-ene (DBN), and 1,5,7-triazabicyclo[4.4.0]-dec-5-ene (TBD) also showed good to very high reactivity.

Formula: C6H4BrClO2S, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Recommanded Product: 3-Chlorophenylacetic acid.

Babin, Victor;Talbot, Alex;Labiche, Alexandre;Destro, Gianluca;Del Vecchio, Antonio;Elmore, Charles S.;Taran, Frederic;Sallustrau, Antoine;Audisio, Davide research published 《 Photochemical Strategy for Carbon Isotope Exchange with CO₂》, the research content is summarized as follows. A photocatalytic approach for carbon isotope exchange is reported. Utilizing [¹³C]CO₂ and [¹⁴C]CO₂ as primary C1 sources, this protocol allows the insertion of the desired carbon isotope into Ph acetic acids without the need for structural modifications or prefunctionalization in one single step. The exceptionally mild conditions required for this traceless transformation are in stark contrast with those for previous methods requiring the use of harsh thermal conditions.

Recommanded Product: 3-Chlorophenylacetic acid, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., 1878-65-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Recommanded Product: 2,3-Dichlorobenzaldehyde.

Babbs, Arran;Berg, Adam;Chatzopoulou, Maria;Davies, Kay E.;Davies, Stephen G.;Edwards, Benjamin;Elsey, David J.;Emer, Enrico;Guiraud, Simon;Harriman, Shawn;Lecci, Cristina;Moir, Lee;Peters, David;Robinson, Neil;Rowley, Jessica A.;Russell, Angela J.;Squire, Sarah E.;Tinsley, Jonathon M.;Wilson, Francis X.;Wynne, Graham M. research published 《 2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy》, the research content is summarized as follows. Utrophin modulation is a promising therapeutic strategy for Duchenne muscular dystrophy (DMD), which should be applicable to all patient populations. Following on from ezutromid, the first-generation utrophin modulator, we describe the development of a second generation of utrophin modulators, based on the bioisosteric replacement of the sulfone group with a phosphinate ester and substitution of the metabolically labile naphthalene with a haloaryl substituent. The improved physicochem. and absorption, distribution, metabolism, and excretion (ADME) properties, further reflected in the enhanced pharmacokinetic profile of the most advanced compounds, 30 and 27, led to significantly better in vivo exposure compared to ezutromid and alleviation of the dystrophic phenotype in mdx mice. While 30 was found to have dose-limiting hepatotoxicity, 27(I) and its enantiomers exhibited limited off-target effects, resulting in a safe profile and highlighting their potential utility as next-generation utrophin modulators suitable for progression toward a future DMD therapy.

6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., Recommanded Product: 2,3-Dichlorobenzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Application of C7H4Cl2O.

Awasthi, Annapurna;Yadav, Pushpendra;Tiwari, Dharmendra Kumar research published 《 A three-component, general and practical route for diastereoselective synthesis of aza-spirocyclic pyrazolones via a decarboxylative annulation process》, the research content is summarized as follows. An efficient, general, and practical route for highly diastereoselective synthesis of aza-spirocyclic pyrazolones from easily available α-amino acids, aldehydes, and alkylidene pyrazolones by means of a decarboxylative annulation process is reported. This high-yielding reaction proceeds through a [3+2]-cycloaddition reaction between alkylidene pyrazolones and a nonstabilized azomethine ylide generated in situ. This method provides easy and smooth access to a variety of highly functionalized aza-spirocyclic pyrazolones in excellent yields (up to 96%). The obtained spiro-pyrazolones comprise four contiguous stereogenic centers including a quaternary carbon center.

Application of C7H4Cl2O, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. COA of Formula: C7H8ClN.

Asakawa, Daiki;Saikusa, Kazumi research published 《 Characterization of the Internal Energy of Ions Produced by Electrospray Ionization Using Substituted Benzyl Ammonium Thermometer Ions》, the research content is summarized as follows. We propose the use of substituted benzyl ammonium species as thermometer ions to characterize the internal energy distribution of the ions produced by electrospray ionization (ESI). Crucially, we found that the activation of the benzyl ammonium species preferentially provided a benzyl cation via N-Cα bond cleavage. In addition, calculations at the CCSD(T)/cc-PVTZ//M06-2X-D3/6-311++G(d,p) level of theory revealed that the threshold energies of fragmentation of the tested model ions ranged from 86 to 192 kJ mol^-1, significantly lower than those of conventional 4-substituted benzylpyridinium thermometer ions. Thus, the substituted benzyl ammoniums are suitable for the characterization of the ESI process under typical exptl. conditions. Further, the internal energies of the ions were found to depend on the radiofrequency voltage of the ion funnel, which is used to increase the transport efficiency of the ions from atm. to vacuum conditions. Our reported method will aid the determination of the optimum ion-funnel radiofrequency voltage for the anal. of small mols. such as metabolites. Furthermore, benzyl ammoniums are com. available, which will facilitate the routine and widespread measurement of the internal energy distributions of ions.

COA of Formula: C7H8ClN, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Computed Properties of 3900-89-8.

Asaba, Ken Nunettsu;Adachi, Yohei;Tokumaru, Kazuyuki;Watanabe, Akira;Goto, Yasufumi;Aoki, Takumi research published 《 Structure-activity relationship studies of 3-substituted pyrazoles as novel allosteric inhibitors of MALT1 protease》, the research content is summarized as follows. We report the discovery of a novel series of 1,5-bisphenylpyrazoles as potent MALT1 inhibitors. Structure-activity relationship exploration of a hit compound led to a potent MALT1 inhibitor. Compound 33 showed strong activity against MALT1 (IC50: 0.49μM), potent cellular activity (NF-κB inhibition and inhibition of IL2 production), and high selectivity against caspase-3, -8, and -9. The results of a kinetics study suggest that compound 33 is a non-competitive inhibitor of MALT1 protein.

3900-89-8, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., Computed Properties of 3900-89-8

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Product Details of C6H4BrClO2S.

Arshad, Mohammad;Beg, Amjad Md;Abdul R Bhat;Athar, Fareeda research published 《 Synthesis, structure elucidation and antibacterial screening of some novel 1,3,4-oxadiazoline derivatives》, the research content is summarized as follows. A novel sequence of 1,3,4-oxadiazoline derivatives has been synthesized with an endeavour to explore their consequence on in vitro growth of microbes causing the microbial contagion. In vitro antimicrobial activity has been performed against the Escherichia coli (E. coli) and Proteus mirabilis (P. mirabilis) which are Gram-neg. (Gram-ve) and Staphylococcus aureus (S. aureus) and Staphylococcus epidermidis (S. epidermis) which are Gram-pos. (Gram+ve) by using disk diffusion method. The min. inhibitory concentration (MIC) has been distinguished by employing the double dilution method. The result of percent inhibition area/μg of the compounds has been differentiated with the standard drug “Ciprofloxacin”. Several compounds portray excellent activity as compared to the standard drug Ciprofloxacin while some of them presented a considerable zone of inhibition. The evaluated compounds for cytotoxicity effects via Human hepatocellular carcinoma (HepG2) cell line by MTT-assay and findings reveal that the exptl. compounds display a viability of ≥80% at 100μM. In mol. docking studies, the 1,3,4-oxadiazoline derivatives demonstrate the ligand-receptor interaction with amino acids which exist on the active sites of the peptide deformylase and the 1,3,4-oxadiazoline derivatives exhibit their antibacterial potential as peptide deformylase inhibitors.

Product Details of C6H4BrClO2S, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics