Ambala, Srinivas; Singh, Rohit; Singh, Maninder; Cham, Pankaj Singh; Gupta, Ria; Munagala, Gurunadham; Yempalla, Kushalava Reddy; Vishwakarma, Ram A.; Singh, Parvinder Pal published the artcile< Metal-free, room temperature, acid-K2S2O8 mediated method for the nitration of olefins: an easy approach for the synthesis of nitroolefins>, Application In Synthesis of 5153-70-8, the main research area is alkene sodium nitrate potassium persulfate TFA promoter diastereoselective nitration; nitroalkene preparation.
A simple, room temperature method for the nitration of olefins by using inexpensive sodium nitrite as a source of nitro groups in the presence of trifluoroacetic acid (TFA) and potassium persulfate (K2S2O8) under an open atm. Styrenes and mono-substituted olefins give stereo-selective corresponding E-nitroolefins under optimized conditions, however, 1,1-bisubstituted olefins give a mixture of E- and Z-nitroolefins. The optimized conditions work well with electron-donating, electron-withdrawing, un-substituted and heterocyclic styrenes and mono-substituted olefins and gave corresponding nitroolefins with good to excellent yields.
RSC Advances published new progress about Alkenes, nitro Role: SPN (Synthetic Preparation), PREP (Preparation). 5153-70-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClNO2, Application In Synthesis of 5153-70-8.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics