Golovchinskaya, E. S.; Nikolaeva, L. A.; Ovcharova, I. M.; Chaman, E. S. published the artcile< Research in the field of purine derivatives. Synthesis of various 9-methyl derivatives of purine from uric acid>, Formula: C6H4Cl2N4, the main research area is .
Heating uric acid with Ac2O resulted in splitting of the imidazole ring to give a mixture of 4,5-diacetamidouracil and its N5-acetyl derivative; further treatment with Me2SO4 and heating the aqueous solution with HCl yielded methylisocaffeine (I); chlorination of I gave 8-trichloromethyl-3-chloromethyl-1,9-dimethylisoxanthine which upon hydrolysis gave 1,9-dimethylisoxanthme (II); boiling II with POCl3 4-5 hrs. and subsequent treatment with PCl5 yielded 2,6-dicloro-9-methylpurine (III) in 60% yields; chlorination of II with PCl5 gave a mixture of III and 2,6,8-trichloro-9-methylpurine.
Puti Sinteza i Izyskuniya Protivoopukholevykh Preparatov, Tr. Simpoziuma po Khim. Protivoopukholevykh Veshchestv, Moscow published new progress about 2382-10-7. 2382-10-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C6H4Cl2N4, Formula: C6H4Cl2N4.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics