Marc, Julia; Sylvestre, Julia; Bemont, Bernard published the artcile< Preparation of cyclopropane acids from γ-lactones>, COA of Formula: C10H9ClO2, the main research area is .
Cyclization of γ-chlorinated esters, readily obtained from the corresponding lactones, gave good yields of esters of cyclopropanecarboxylic acid by treatment with bases under anhydrous conditions. Thus, with tert-AmONa or PhCMe2ONa in C6H6, Cl(CH2)3CO2Et was cyclized to Et cyclopropanecarboxylate; the free acid was characterized as its S-benzylthiuronium salt, m. 161°. Similarly, the anilide of 2-methylcyclopropanecarboxylic acid, m. 109°, resulted from the Et ester of the latter, produced from MeCHCl(CH2)2CO2Et. From BzCH2CH2CO2H was obtained γ-phenyl-γ-butyrolactone, converted by SOCl2 in C6H6 to PhCHClCH2CH2CO2Et, which, boiled with Me3-COK several hrs. and the solution washed with KMnO4 to remove olefinic compounds and distilled yielded Et 2-phenylcyclopropanecarboxylate, b0.2 105-6°, m. 38° (petr. ether); hydrolysis of the ester produced the free trans acid, m. 90° (anilide, m. 145°). Analogous procedures yielded 2-(p-chlorophenyl)cyclopropanecarboxylic acid, m. 112°; p-BrC6H4 analog, m. 122°; p-MeOC6H4 analog, m. 112° (Et ester, m. 79°). The latter compounds were prepared by condensation of succinic anhydride with the aromatic derivatives, reduction to the lactones, and conversion of the latter to the cyclopropanecarboxylic acids.
Compt. rend. published new progress about Lactones. 90940-40-2 belongs to class chlorides-buliding-blocks, and the molecular formula is C10H9ClO2, COA of Formula: C10H9ClO2.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics