Pandit, Neelanjana; Shah, Kamal; Agrawal, Neetu; Upmanyu, Neeraj; Shrivastava, Sushant K.; Mishra, Pradeep published the artcile< Synthesis, characterization and biological evaluation of some novel fluoroquinolones>, Recommanded Product: 5-(3-Chlorophenyl)-1,3,4-thiadiazol-2-amine, the main research area is fluoroquinolone thiadiazole derivative preparation bactericide fungicide.
Different derivatives of fluoroquinolones were synthesized by combining them with different thiadiazoles. The synthesized compounds were characterized by IR spectroscopy, proton NMR and mass spectral data. The compounds were screened for their antibacterial and antifungal activity. Ciprofloxacin thiadiazole 7c (I) showed good antibacterial as well as antifungal activities, whereas 13c and 13e (II; R1 = Cl, R2 = H and R1 = R2 = OMe, resp.) showed antibacterial and antifungal activity resp. Sparfloxacin derivative 8c (III) showed both antibacterial and antifungal activity. Sparfloxacin derivatives 14b and 14e (IV; R1 = H, R2 = Cl and R1 = R2 OMe) showed antibacterial and antifungal activity resp.
Medicinal Chemistry Research published new progress about Antibacterial agents. 70057-67-9 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClN3S, Recommanded Product: 5-(3-Chlorophenyl)-1,3,4-thiadiazol-2-amine.
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics