Yao, Yongqi; Su, Shaoting; Wu, Nan; Wu, Wanqing; Jiang, Huanfeng published the artcile< The cobalt(II)-catalyzed acyloxylation of picolinamides with bifunctional silver carboxylate via C-H bond activation>, Synthetic Route of 672948-03-7, the main research area is picolinamide silver carboxylate cobalt catalyst acyloxylation; acyloxy naphthalenyl picolinamide regioselective preparation.
The cobalt(II)-catalyzed C-H bond acyloxylation of picolinamides with bifunctional silver carboxylate was developed. The operationally simple acyloxylation allowed us to efficiently synthesize 8-functionalized 1-naphthylamine (up to 94% yield) under mild conditions without any addnl. oxidant and base additives. Control experiments were performed to investigate the mechanism of the reaction. This mild and practical acyloxylation approach provide an efficient route for accessing highly functionalized polysubstituted naphthalene compounds and a pathway for modifying drug mols. and natural products.
Organic Chemistry Frontiers published new progress about Acyloxylation (regioselective). 672948-03-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C4H3NO3, Synthetic Route of 672948-03-7.
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics