《Colorimetric screening of bacterial enzyme activity and inhibition based on the aggregation of gold nanoparticles》 was written by Jiang, Tingting; Liu, Rongrong; Huang, Xianfeng; Feng, Huajun; Teo, Weiling; Xing, Bengang. Category: chlorides-buliding-blocks And the article was included in Chemical Communications (Cambridge, United Kingdom) on April 21 ,2009. The article conveys some information:
A simple and novel gold nanoparticle (Au-NPs) based colorimetric method has been developed for efficient screening of class A β-lactamase (Bla) activity and inhibitors in vitro and in bacterial strains. In the experiment, the researchers used many compounds, for example, (6R,7R)-Benzhydryl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride(cas: 79349-53-4Category: chlorides-buliding-blocks)
(6R,7R)-Benzhydryl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride(cas:79349-53-4) is one of azetidine.Azetidines (azacyclobutanes) constitute a well-known class of heterocyclic compounds. Azetidine scaffold has been discovered in several natural products.Category: chlorides-buliding-blocks Several pharmacologically important synthetic compounds also contain azetidine ring. Because of inherent ring strain, the synthesis of azetidines is a challenging endeavor.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics