Shu, Liwei; Ren, Lulu; Wang, Yuchen; Fang, Tao; Ye, Zhijian; Han, Weidong; Chen, Chao; Wang, Hangxiang published the artcile< Niacin-ligated platinum(IV)-ruthenium(II) chimeric complexes synergistically suppress tumor metastasis and growth with potentially reduced toxicity in vivo>, SDS of cas: 67421-02-7, the main research area is antitumor niacin platinum ruthenium chimeric complexes synergy metastasis proliferation.
Niacin-ligated platinum(IV)-ruthenium(II) chimeric complexes have been synthesized and evaluated for their antitumor performance. The water-soluble optimal complex was shown to be a chimeric prodrug that not only potently inhibits the metastasis and proliferation of tumor cells but also has an unexpectedly higher safety margin in animals compared with the traditionally-used, clin. approved drug cisplatin.
Chemical Communications (Cambridge, United Kingdom) published new progress about Antitumor agents. 67421-02-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C24H36Cl4Ru2, SDS of cas: 67421-02-7.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics