Alam, Faruk published the artcile< A study on the antimicrobial and antioxidant activities of some new 1, 3, 4-thiadiazole derivatives>, Application In Synthesis of 70057-67-9, the main research area is thiadiazole derivative antioxidant antimicrobial agent.
The various derivatives of thiadiazole were prepared by the reaction of m-chlorophenyl isocyanate and p-chlorophenyl isocyanate with 5-(substituted phenyl) -2-amino-1, 3, 4-thiadiazole in dry acetonitrile. Elemental anal., IR, 1H NMR, mass spectral data confirmed the structure of the newly synthesized compounds All the derivatives of these moieties were evaluated for invitro antimicrobial and invitro antioxidant activity. Most of the synthesized compounds showed potent antimicrobial activity at 100 and 50 μg/mL and antioxidant scavenging activity. Compounds showed most significant antibacterial activity against gram pos. test organism S.aureus and most significant antifungal activity against test organisms Aspergillus niger and Candida albicans. All the compounds were screened for in vitro antioxidant activity by various methods as Scavenging of DPPH, Scavenging of nitric oxide radical inhibitory activity.
International Journal of ChemTech Research published new progress about Antimicrobial agents. 70057-67-9 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClN3S, Application In Synthesis of 70057-67-9.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics