《Controlled synthesis of N,N-dimethylarylsulfonamide derivatives as nematicidal agents》 was published in Journal of Asian Natural Products Research in 2020. These research results belong to Chen, Gen-Qiang; Xia, Yan-Fei; Yang, Jin-Ming; Che, Zhi-Ping; Sun, Di; Li, Shen; Tian, Yue-E.; Liu, Sheng-Ming; Jiang, Jia; Lin, Xiao-Min. HPLC of Formula: 16629-19-9 The article mentions the following:
Gramine could be intelligently and efficiently supplied with N,N-dimethylamino group and then reacted with the corresponding sulfonyl chlorides to synthesize N,N-dimethylarylsulfonamides I [R = Ph, 4-FC6H4, 2-thienyl, etc.]. Herein designed and controlled synthesis of N,N-dimethylarylsulfonamide derivatives and first reported the results of the nematicidal activity of N,N-dimethylarylsulfonamide compounds against Meloidogyne incongnita in vitro, resp. Among all of the N,N-dimethylarylsulfonamide derivatives, compounds I [R = Ph, 4-MeOC6H4, 4-O2NC6H4, 8-quinolyl] exhibited potent nematicidal activity with median lethal concentration (LC50) values ranging from 0.22 to 0.26 mg/L. Most noteworthy, compounds I [R = 4-MeOC6H4, 8-quinolyl] showed the best promising and pronounced nematicidal activity, with LC50 values of 0.2381 and 0.2259 mg/L, resp. The experimental process involved the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9HPLC of Formula: 16629-19-9)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. HPLC of Formula: 16629-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics