Chen, Jinjin; Chang, Dan; Xiao, Fuhong; Deng, Guo-Jun published the artcile< Three-Component Ordered Annulation of Amines, Ketones, and Nitrovinylarenes: Access to Fused Pyrroles and Substituted Indoles under Metal-Free Conditions>, Category: chlorides-buliding-blocks, the main research area is fused pyrrole indole preparation; cyclocondensation cyclic ketone amine nitrostyrene; cyclohexanone arylamine nitrostyrene cyclocondensation aerobic aromatization iodine catalyst.
Ketones, primary amines such as aniline, and β-nitrostyrenes such as (E)-PhCH:CHNO2 underwent cyclocondensation reactions in toluene at 150° to yield fused pyrroles such as I [R = Me, Et, n-Pr, BuCH2, t-Bu, EtCMe2, Ph, 4-HOC6H4, EtO2C, AcNH, BocNH; X = (CH2)n, CHR, Me2C; n = 1, 2, 3, 7]. Thermal cyclocondensation of cyclohexanones, arylamines, and nitrostyrenes followed by aromatization with O2 and DMSO in the presence of I2 yielded indoles in 50-75% yields.
Journal of Organic Chemistry published new progress about Alkenes, nitro Role: RCT (Reactant), RACT (Reactant or Reagent). 5153-70-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClNO2, Category: chlorides-buliding-blocks.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics