Hong, Cynthia M.; Whittaker, Aaron M.; Schultz, Danielle M. published the artcile< Nucleophilic Fluorination of Heteroaryl Chlorides and Aryl Triflates Enabled by Cooperative Catalysis>, Synthetic Route of 2382-10-7, the main research area is heteroaryl chloride crown ether catalyst nucleophilic fluorination; heteroaromatic fluoride preparation; phenyl triflate crown ether catalyst nucleophilic fluorination; fluorobenzene preparation.
A new approach that leverages the cooperative action of 18-crown-6 ether and tetramethylammonium chloride to catalytically access the reactivity of tetramethylammonium fluoride and achieve halex fluorinations under mild conditions with operational ease was reported. The described methodol. readily converts both heteroaryl chlorides and aryl triflates to their corresponding (hetero)aryl fluorides in high yields and purities.
Journal of Organic Chemistry published new progress about Aryl chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 2382-10-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C6H4Cl2N4, Synthetic Route of 2382-10-7.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics