Computed Properties of C8H6Cl2O3On March 31, 2002, Kousaka, Takeshi; Mori, Kenji published an article in Bioscience, Biotechnology, and Biochemistry. The article was 《Synthesis of (1R,2S)-1-(3′-Chloro-4′-methoxyphenyl)-1,2-propanediol (Trametol) and (1R,2S)-1-(3′,5′-dichloro-4′-methoxyphenyl)-1,2-propanediol, chlorinated fungal metabolites in the natural environment》. The article mentions the following:
(1R,2S)-1-(3′-Chloro-4′-methoxyphenyl)-1,2-propanediol (trametol), a metabolite of the fungus Trametes sp. IVP-F640 and Bjerkandera sp. BOS55, was synthesized by employing Sharpless asym. dihydroxylation as the key step. Similarly, the (1R,2S)-isomer of 1-(3′,5′-dichloro-4′-methoxyphenyl)-1,2-propanediol, another metabolite of Bjerkandera sp. BOS55, was synthesized by asym. dihydroxylation. The experimental process involved the reaction of 3,5-Dichloro-4-methoxybenzoic acid(cas: 37908-97-7Computed Properties of C8H6Cl2O3)
3,5-Dichloro-4-methoxybenzoic acid(cas: 37908-97-7) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Computed Properties of C8H6Cl2O3
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics