Kowalczyk, Bruce A. published the artcile< Synthesis of (dihalophenyl)acetic acids using aromatic nucleophilic substitution strategy>, COA of Formula: C6H3ClF2, the main research area is halophenylacetate preparation; acetate dihalophenyl preparation; fluorophenylacetate preparation; fluorohalobenzene cyanoacetate aromatic nucleophilic substitution.
A simple synthetic strategy to (dihalophenyl)acetates and specifically (3,5-difluorophenyl)acetate an important pharmaceutical intermediate was developed. The aromatic nucleophilic substitution of dihalofluorobenzenes using the anion of cyanoacetate yielded (dihalophenyl)cyanoacetates. Basic decarboxylation of the latter produced targeted (dihalophenyl)acetates.
Synthesis published new progress about Aryl fluorides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1435-43-4 belongs to class chlorides-buliding-blocks, and the molecular formula is C6H3ClF2, COA of Formula: C6H3ClF2.
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics