Koyama, Hiroo; Boueres, Julia K.; Miller, Daniel J.; Berger, Joel P.; MacNaul, Karen L.; Wang, Pei-ran; Ippolito, Marc C.; Wright, Samuel D.; Agrawal, Arun K.; Moller, David E.; Sahoo, Soumya P. published the artcile< (2R)-2-Methylchromane-2-carboxylic acids: Discovery of selective PPARα agonists as hypolipidemic agents>, Product Details of C7H4ClF3O, the main research area is chromanecarboxylate preparation PPARalpha hypolipidemic SAR.
A SAR study was conducted on chromane-2-carboxylic acid toward selective PPARα agonism. As a result, highly potent, and selective PPARα agonists were discovered. The optimized compound I exhibited robust lowering of total cholesterol levels in hamster and dog animal models.
Bioorganic & Medicinal Chemistry Letters published new progress about Glycerides Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 35852-58-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H4ClF3O, Product Details of C7H4ClF3O.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics