Lou, Qin-Xin; Li, Jing-Yu; Yang, Shang-Dong published the artcile< Iridium(III)-Catalyzed C-H Functionalization of Triarylphosphine Oxides with Diazo Dicarbonyl Compounds: Synthesis of α-Aryl 1,3-Dicarbonyl Derivatives>, Application In Synthesis of 17082-09-6, the main research area is arylated dicarbonyl compound preparation iridium catalyst; triarylphosphine oxide diazo dicarbonyl compound arylation; di ketone acyl chloride acetamidobenzenesulfonyl azide diazotization.
A novel (pentamethylcyclopenta-1,3-dienyl)iridium(III)-catalyzed direct C-H functionalization of triarylphosphine oxides with diazo dicarbonyl compounds through carbene insertion has been developed. This strategy provides a simple and efficient route to the construction of α-arylated 1,3-dicarbonyl compounds I (R1 = Me, Ph, 4-FC6H4, etc.; R2 = Ph, 3-MeC6H4, 2-thienyl, etc.; R3 = t-Bu, Ph, 2-naphthyl, etc.; R4 = Me, OEt, t-Bu, etc.; R = H, 4-Me, 5-OMe, etc.) which are important building blocks in pharmaceutical chem.
Synlett published new progress about 1,3-Dicarbonyl compounds Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Application In Synthesis of 17082-09-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics