Mohan, Jag; Anjaneyulu, G. S. R.; Kiran published the artcile< Heterocyclic systems containing a bridge-head nitrogen atom: reactions of 2-aminothiadiazoles with α-haloketones and ketones in the presence of NBS>, Recommanded Product: 5-(3-Chlorophenyl)-1,3,4-thiadiazol-2-amine, the main research area is antimicrobial diarylimidazothiadiazole bromo; imidazothiadiazole diaryl bromo preparation antimicrobial.
Diarylimidazo[2,1-b]-1,3,4-thiadiazoles I (R = Cl, R1 = H, Br, Me, Ph, Cl; R = Me, R1 = Cl, Ph) are prepared by the reaction of α-haloketones with 2-aminothiadiazoles II, or more conveniently, by treating II directly with ketones in the presence of NBS. Bromination of I (R = R1 = Cl) furnishes a 5-bromo-2,6-diarylimidazo[2,1-b]thiadiazole derivative The antimicrobial activity of I (R = R1 = Cl) and a derivative has been evaluated; they were found to be inactive.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 70057-67-9. 70057-67-9 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClN3S, Recommanded Product: 5-(3-Chlorophenyl)-1,3,4-thiadiazol-2-amine.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics