Oxoby, Mayalen; Moreau, Francois; Durant, Lionel; Denis, Alexis; Genevard, Jean-Marie; Vongsouthi, Vanida; Escaich, Sonia; Gerusz, Vincent published the artcile< Towards Gram-positive antivirulence drugs: New inhibitors of Streptococcus agalactiae Stk1>, Recommanded Product: 2,6-Dichloro-9-methyl-9H-purine, the main research area is preparation structure antibacterial antivirulence inhibitor Streptococcus agalactiae Stk1.
A structure-activity relationship study from a screening hit and structure-based design strategy has led to the identification of bisarylureas as potent inhibitors of Streptococcus agalactiae Stk1. As this target has been directly linked to bacterial virulence, these inhibitors can be considered as a promising step towards antivirulence drugs.
Bioorganic & Medicinal Chemistry Letters published new progress about Antibacterial agents. 2382-10-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C6H4Cl2N4, Recommanded Product: 2,6-Dichloro-9-methyl-9H-purine.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics