Shi, Chengcheng; Guo, Lin; Gao, Han; Luo, Mengqi; Yang, Chao; Xia, Wujiong published the artcile< Highly Diastereoselective Synthesis of γ-Lactams Enabled by Photoinduced Deaminative [3 + 2] Annulation Reaction>, Category: chlorides-buliding-blocks, the main research area is gamma lactam diastereoselective preparation; aminopyridinium alkene photochem cycloaddition.
The photoinitiated deaminative [3 + 2] annulation reaction of N-aminopyridinium salts with alkenes for the synthesis of functionalized γ-lactams is described. This transformation shows good functional group tolerance as well as excellent diastereoselectivity. Preliminary studies suggest that the employed N-aminopyridinium salts generate the key amidyl radical intermediates through N-N bond cleavage via a photoinduced single-electron transfer (SET) process. The amidyl radical species would add to the double bond of alkenes, followed by a radical-mediated annulation process, to afford the desired γ-lactams.
Organic Letters published new progress about [3+2] Cycloaddition reaction catalysts (photochem.). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Category: chlorides-buliding-blocks.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics