Tryniszewski, Michal; Barbasiewicz, Michal published the artcile< Gram-Scale Preparation of Acyl Fluorides and Their Reactions with Hindered Nucleophiles>, HPLC of Formula: 17082-09-6, the main research area is acyl fluoride preparation reaction with hindered nucleophile; aqueous bifluoride acyl chloride halogen exchange.
A series of acyl fluorides was synthesized at 100 mmol scale using phase-transfer-catalyzed halogen exchange between acyl chlorides and aqueous bifluoride solution The convenient procedure consists of vigorous stirring of the biphasic mixture at room temperature, followed by extraction and distillation Isolated acyl fluorides (usually 7-20 g) display excellent purity and can be transformed into sterically hindered amides and esters when treated with lithium amide bases and alkoxides under mild conditions.
Synthesis published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, HPLC of Formula: 17082-09-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics