Zhao, Zhe; Tian, Xinzhe; Tang, Peichen; Ren, Yun-Lai; Zhao, Shuang; Zheng, Xianfu; Cheng, Xinqiang published the artcile< Autocatalytic Friedel-Crafts Acylation of Arenes without Additional Catalyst and Additive>, Formula: C9H7ClO, the main research area is acyl chloride arene autocatalysis regioselective Friedel Crafts acylation; aryl ketone preparation.
A new and autocatalytic method was developed for Friedel-Crafts acylation of arenes without addnl. catalyst and additive. A series of electron-rich arenes underwent the acylation to give the targeted product in low to high yields by using aryl, alkyl and vinyl acyl chlorides as the acylating reagent, which gave an effective method for the preparation of diaryl ketones, alkyl aryl ketones and α,β-unsaturated ketones. Preliminary mechanistic investigation suggested that the present acylation displayed an induction period and a sigmoid kinetic profile characteristic of autocatalytic systems, and the resulting H+ played a role of the catalyst.
ChemistrySelect published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Formula: C9H7ClO.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics