Bi, Qing-wei; Shi, Zhi-chuan; Zhao, Zhi-gang; Xia, Zhen-yang published the artcile< Synthesis of novel thiadiazoles type molecular tweezers based on hyodeoxycholic acid promoted by microwave irradiation>, Electric Literature of 70057-67-9, the main research area is thiadiazole mol tweezer hyodeoxycholic acid microwave preparation.
Ten novel steroidal mol. tweezers are efficiently synthesized via microwave irradiation by using hyodeoxycholic acid as spacer and 1, 3, 4-thiadiazoles unit as arm. Compared with a conventional method, the yields are increased from 38%∼48% to 80%∼91% and the reaction time is reduced from 1800-2400 min to 40-50 min. The structures of these novel mol. tweezers are characterized by 1H NMR, IR, ESI-MS spectra and elemental anal. The recognition properties of these mol. tweezers for D/L-Leu-OMe and D/L-Phe-OMe are investigated by UV-vis spectra. The result indicates that this type of mol. tweezers has good binding properties for D-amino acid Me esters.
Xinan Minzu Daxue Xuebao, Ziran Kexueban published new progress about Complexing agents. 70057-67-9 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClN3S, Electric Literature of 70057-67-9.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics