Chen, Xiaohong; Liu, Xiaoguang; Martinez, Jenny S.; Mohr, Justin T. published the artcile< Practical regioselective halogenation of vinylogous esters: synthesis of differentiated mono-haloresorcinols and polyhalogenated resorcinols>, Electric Literature of 42413-03-6, the main research area is regioselective halogenation vinylogous ester; synthesis differentiated haloresorcinol polyhalogenated resorcinol.
A practical and efficient method for the direct, regioselective conversion of vinylogous esters to haloresorcinols is reported. Control of the reaction conditions enables synthesis of either the 4- or 6-haloresorcinol isomers from a common precursor with excellent regiocontrol and high yield. The generality and functional group tolerance of this novel protocol is demonstrated. The utility of this methodol. to access polyhaloresorcinols is also reported. These methods create useful functionalized building blocks for further synthetic applications.
Tetrahedron published new progress about Esters Role: RCT (Reactant), RACT (Reactant or Reagent) (vinylogous). 42413-03-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H6Cl2O2S, Electric Literature of 42413-03-6.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics