Emokpae, Thomas A.; Eguavuen, Osa; Hirst, Jack published the artcile< The kinetics of the reactions of picryl chloride, with some substituted anilines. Part 5>, Synthetic Route of 29027-20-1, the main research area is picryl chloride substitution aniline kinetics; substituent effect aniline substitution; additivity aniline substitution picryl.
Arrhenius parameters were determined for the reactions of picryl chloride in MeCN with 3,5-RR1C6H3NH2 [R = H2N, Me, R1 = H; R = H2N, R1 = O2N (I); R = F, R1 = MeSO2; R = NO2, OMe, Me, F, Cl, Br, iodo, R1 = Me; R = R1 = F, Cl, Br, iodo]. A total of 33 3,5-disubstituted anilines was examined for the additivity of substituent effects on the free energy of activation, and, with the exception of I, this hypothesis reproduces exptl. rate constants within a factor of 2. A rationalization is proposed for the deviations that occur in some cases when more stringent criteria of additivity are used.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) published new progress about Additivity. 29027-20-1 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H8ClN, Synthetic Route of 29027-20-1.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics