Karuvalam, Ranjith P.; Haridas, Karickal R.; Nayak, Susanta K.; Guru Row, Tayur N.; Rajeesh, P.; Rishikesan, R.; Kumari, N. Suchetha published the artcile< Design, synthesis of some new (2-aminothiazol-4-yl)methylester derivatives as possible antimicrobial and antitubercular agents>, SDS of cas: 90940-40-2, the main research area is aminothiazolylmethyl ester carboxylic acid preparation antimicrobial antitubercular; ester aminothiazolylmethyl preparation antimicrobial antitubercular; thiazolylmethyl ester carboxylic acid preparation antimicrobial antitubercular; crystal structure aminothiazolylmethyl ester chlorophenylcyclopropanoic acid.
A series of 20 (2-aminothiazol-4-yl)methylester derivatives were synthesized in good yields and characterized by 1H NMR, 13C NMR, mass spectral and elemental analyses. The crystal structure of I was determined and data are referenced. The compounds were evaluated for their preliminary in vitro antibacterial, antifungal activity and were screened for antitubercular activity against Mycobacterium tuberculosis H37Rv strain. The synthesized compounds displayed interesting antimicrobial activity.
European Journal of Medicinal Chemistry published new progress about Antimicrobial agents. 90940-40-2 belongs to class chlorides-buliding-blocks, and the molecular formula is C10H9ClO2, SDS of cas: 90940-40-2.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics